Recent research demonstrates probiotics may benefit brain health, including cognitive function, and prevent cognitive decline. These live microorganisms, also known as "good bugs," are defined by their health benefits for the host. Research indicates that the gut and brain are interconnected through a partnership called the gut-brain axis. Some studies have found that probiotics may help boost mood and cognitive function and lower stress. For instance, certain probiotics have been associated with improved cognitive function and mood in older adults.
There are approximately 8,000 strains of probiotics that have been identified, and research into the different strains is constantly evolving. Let's explore the strains that may contribute to our behavior and cognitive function and prevent cognitive decline.
Probiotics and Behavior
Recent research has unveiled the fascinating influence of gut microbes, modulated by probiotics, in creating "neuroactive" compounds such as serotonin, tryptophan, and GABA. These compounds play pivotal roles in human health, including cognitive function, mood regulation, and stress management. For instance, low serotonin levels have been associated with poor memory and depressed mood, highlighting the significance of these neuroactive compounds. Moreover, the impact of our gut microbiome on our risk-taking behavior and decision-making processes has been a subject of scientific interest. Intriguingly, a study revealed that individuals taking probiotics demonstrated a propensity for more calculated risks and future-focused decision-making.
Tryptophans, which serve as precursors to serotonin and melatonin, help regulate the sleep-wake cycle, also known as the circadian rhythm. On the other hand, GABA, a calming neurotransmitter, plays a crucial role in inhibiting impulses and aiding in anxiety management. Specific probiotic species or strains, such as Lactobacillus helveticus and Bifidobacterium longum have been shown to increase serotonin levels and improve mood. Bifidobacterium longum has also exhibited the potential to balance the stress hormone cortisol and alleviate anxiety.
Additionally, strains like Bifidobacterium lactis, Enterococcus faecium, Lactobacillus acidophilus, Lactobacillus brevis, Lactococcus lactis, Lactobacillus brevis LB0, Lactobacillus plantarum 299v, Lactobacillus rhamnosus, and Lactobacillus reuteri have been associated with GABA production, influencing focus, attention, and communication skills.
These probiotics impact how we navigate the world and engage in social interactions. They may also play a role in stress management. The potential of probiotics to enhance behavior is a rapidly evolving area of study that holds a lot of promise.
Probiotics for Cognitive Function
Recent research has looked at the state of the gut microbiome on memory, cognitive function, and the potential to prevent cognitive decline. Studies have identified specific probiotic strains, such as Lactobacillus rhamnosus GG, which shows promise in preventing age-related memory and cognitive decline. Furthermore, a combination of strains including Lactobacillus acidophilus, L. fermentum, Bifidobacterium lactis, and B. longum has been associated with improvements in memory and learning deficits.
Throughout our lives, the composition of our microbiome is in a constant state of flux. As we age, changes in appetite, digestion, and other factors can influence cognition through this bi-directional communication pathway. Emerging evidence suggests that the gut microbiota may be related to the onset and progression of cognitive decline.
Probiotic supplementation has shown promise in improving cognitive function and mood in older adults. A randomized, double-blind, placebo-controlled trial revealed that probiotics led to improvements in cognitive function and mental flexibility in healthy older adults
The Future of Probiotics and Brain Health
Psychobiotics, a term coined in 2013, represent an evolving field of study that explores how various strains of probiotics can influence brain health and be utilized to enhance it. These live microorganisms have been found to exert a significant impact on neurotransmitters, hormones, and immunity, thereby potentially influencing cognitive function and mental well-being
This evolving field holds great promise for advancing our understanding of how probiotic strains may positively influence various aspects of human health, particularly in cognitive function.
Bottom Line
More studies to identify the best strains for specific benefits are happening, and the next few years will help with cognitive and brain health in many ways. Stay tuned.
[Editor’s Note: Kyo-Dopholis has a variety of probiotics for various ages, stages, and conditions. You can learn more about them here.]